Allan I Levey Selected Research

Biomarkers (Surrogate Marker)

5/2024	Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
4/2024	Association between Fine Particulate Matter Exposure and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease among a Cognitively Healthy Population-Based Cohort.
1/2024	Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.
12/2023	Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals.
11/2023	Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease.
1/2023	Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.
1/2023	Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART.
1/2023	Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
1/2023	A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
1/2023	Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.

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Allan I Levey Research Topics

Disease

120	Alzheimer Disease (Alzheimer's Disease) 05/2024 - 06/2003
32	Cognitive Dysfunction 12/2023 - 02/2006
25	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2024 - 01/2004
16	Dementia (Dementias) 12/2023 - 01/2004
15	Parkinson Disease (Parkinson's Disease) 01/2024 - 12/2003
10	Inflammation (Inflammations) 03/2024 - 10/2009
9	Amyloid Plaque 05/2024 - 08/2004
9	Neuroinflammatory Diseases 07/2022 - 01/2017
9	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 11/2013 - 11/2009
7	Tauopathies 05/2024 - 10/2009
7	Disease Progression 01/2020 - 12/2010
6	Frontotemporal Dementia (Semantic Dementia) 01/2021 - 03/2010
3	Hippocampal Sclerosis 06/2022 - 11/2020
3	Intracranial Arteriosclerosis (Cerebral Atherosclerosis) 06/2022 - 01/2020
3	Coronary Artery Disease (Coronary Atherosclerosis) 06/2016 - 08/2012
3	Neuroblastoma 03/2014 - 10/2002
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 08/2012 - 03/2005
2	Amyloid angiopathy 05/2024 - 01/2022
2	Amyloidosis 12/2023 - 01/2022
2	Pathologic Processes 01/2023 - 11/2022
2	Proteostasis Deficiencies 07/2022 - 01/2022
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 06/2022 - 01/2022
2	Mental Disorders (Mental Disorder) 01/2022 - 01/2013
2	Atrophy 01/2022 - 01/2013
2	Atherosclerosis 01/2022 - 08/2012
2	Infarction (Infarctions) 01/2022 - 11/2020
2	Vascular Diseases (Vascular Disease) 01/2022 - 08/2012
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2022 - 08/2012
2	Hypertension (High Blood Pressure) 01/2022 - 08/2010
2	limbic-predominant age-related TDP-43 encephalopathy 01/2022 - 01/2019
2	Corticobasal Degeneration 11/2013 - 08/2012
2	TDP-43 Proteinopathies 01/2012 - 04/2010
2	Seizures (Absence Seizure) 03/2003 - 07/2002
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2023

Drug/Important Bio-Agent (IBA)

71	Proteins (Proteins, Gene)FDA Link 05/2024 - 04/2002
30	Biomarkers (Surrogate Marker)IBA 05/2024 - 08/2004
26	Amyloid (Amyloid Fibrils)IBA 02/2024 - 03/2005
18	ProteomeIBA 02/2024 - 08/2004
14	Apolipoproteins E (ApoE)IBA 03/2024 - 09/2009
10	Amyloid beta-PeptidesIBA 07/2022 - 02/2006
9	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2022 - 03/2010
8	ApolipoproteinsIBA 12/2023 - 08/2004
7	CholesterolIBA 02/2024 - 01/2008
7	Peptides (Polypeptides)IBA 02/2023 - 12/2010
7	RNA (Ribonucleic Acid)IBA 01/2022 - 05/2012
7	LipidsIBA 01/2021 - 01/2008
7	UbiquitinIBA 10/2018 - 03/2004
6	Detergents (Detergent)IBA 01/2021 - 11/2009
5	Cholinesterase Inhibitors (Anticholinesterases)IBA 12/2023 - 09/2002
5	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021 - 01/2012
5	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2017 - 07/2002
4	Particulate MatterIBA 04/2024 - 04/2023
4	Protein AggregatesIBA 10/2018 - 11/2009
3	Carrier Proteins (Binding Protein)IBA 02/2024 - 02/2015
3	Methylphenidate (Ritalin)FDA LinkGeneric 12/2023 - 01/2021
3	tau Proteins (tau Protein)IBA 10/2023 - 10/2009
3	LDL CholesterolIBA 06/2022 - 01/2016
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 01/2013
3	Phosphotransferases (Kinase)IBA 01/2021 - 12/2010
3	U1 Small Nuclear RibonucleoproteinIBA 01/2018 - 04/2014
3	Cholinergic Agents (Cholinergics)IBA 10/2016 - 06/2003
2	AntibodiesIBA 12/2023 - 04/2002
2	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 10/2023 - 01/2022
2	moesinIBA 10/2023 - 01/2020
2	OxylipinsIBA 01/2023 - 01/2021
2	EndocannabinoidsIBA 01/2023 - 01/2021
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2023 - 01/2021
2	Epoxide HydrolasesIBA 01/2023 - 01/2021
2	SugarsIBA 01/2023 - 01/2020
2	SteroidsIBA 01/2023 - 01/2021
2	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 01/2021
2	Messenger RNA (mRNA)IBA 01/2022 - 01/2020
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2021 - 07/2002
2	Potassium Channels (Potassium Channel)IBA 01/2021 - 01/2017
2	IsotopesIBA 01/2019 - 05/2012
2	Cholinergic Antagonists (Anticholinergics)IBA 09/2017 - 08/2003
2	sarkosylIBA 12/2016 - 12/2014
2	Donepezil (Aricept)FDA LinkGeneric 10/2016 - 01/2004
2	HDL CholesterolIBA 06/2016 - 01/2016
2	asparaginylendopeptidase (legumain)IBA 11/2015 - 11/2014
2	Threonine (L-Threonine)FDA Link 02/2015 - 11/2013
2	Small Nuclear Ribonucleoproteins (snRNP)IBA 12/2014 - 04/2014
2	Dichlorodiphenyl Dichloroethylene (DDE)IBA 08/2014 - 03/2014
2	PesticidesIBA 03/2014 - 10/2011
2	Nuclear Proteins (Protein, Nuclear)IBA 07/2013 - 08/2012
2	SynucleinsIBA 06/2013 - 04/2012
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 08/2012 - 12/2010
2	DNA (Deoxyribonucleic Acid)IBA 11/2011 - 12/2010
2	PolyubiquitinIBA 03/2011 - 04/2010
2	LDL Receptors (LDL Receptor)IBA 02/2011 - 08/2004
2	LigandsIBA 08/2010 - 05/2010
2	EnzymesIBA 05/2008 - 03/2005
2	Protein Deglycase DJ-1IBA 01/2007 - 02/2004
2	thioflavin TIBA 01/2006 - 08/2004
2	Pilocarpine (Ocusert)FDA LinkGeneric 03/2003 - 07/2002
1	Heparin (Liquaemin)FDA LinkGeneric 02/2024

Therapy/Procedure

12	Therapeutics 11/2022 - 01/2004
3	Lasers (Laser) 01/2011 - 08/2004
1	Drug Therapy (Chemotherapy) 05/2024
1	Immunotherapy 12/2023